CATH Domain 4f6xA00

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.600	Farnesyl Diphosphate Synthase
	1.10.600.10	Farnesyl Diphosphate Synthase

Superfamily	Farnesyl Diphosphate Synthase
Functional Family	Dehydrosqualene synthase

2.5.1.96

4,4'-diapophytoene synthase.

based on mapping to UniProt A9JQL9

2 (2E,6E)-farnesyl diphosphate = 15-cis-4,4'-diapophytoene + 2 diphosphate.

-!- Typical of Staphylococcus aureus and some other bacteria such as Heliobacillus sp.

CRTM_STAAU

Staphylococcus aureus

4,4'-diapophytoene synthase

PDB	4F6X
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis. Zhang, Y., Lin, F.-Y., Li, K., Zhu, W., Liu, Y.L., Cao, R., Pang, R., Lee, E., Axelson, J., Hensler, M., Wang, K., Molohon, K.J., Wang, Y., Mitchell, D.A., Nizet, V., Oldfield, E. ACS Med Chem Lett