CATH Classification
Level | CATH Code | Description |
---|---|---|
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1 | Mainly Alpha |
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1.20 | Up-down Bundle |
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1.20.58 | Methane Monooxygenase Hydroxylase; Chain G, domain 1 |
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1.20.58.1370 |
Domain Context
CATH Clusters
Superfamily | 1.20.58.1370 |
Functional Family | lysine-specific demethylase 6A isoform X2 |
Enzyme Information
1.14.11.- |
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q5NCY0
|
UniProtKB Entries (1)
Q5NCY0 |
KDM6B_MOUSE
Mus musculus
Lysine-specific demethylase 6B
|
PDB Structure
PDB | 4EZ4 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature
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