CATH Domain 4e8yA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.1190	UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase
	3.40.1190.20	Ribokinase

Domain Context

CATH Clusters

Superfamily	3.40.1190.20
Functional Family	Bifunctional protein HldE

Enzyme Information

UniProtKB Entries (1)

B4EB35_BURCJ

Burkholderia cenocepacia J2315

D-beta-D-heptose 7-phosphate kinase

PDB Structure

PDB	4E8Y
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural-functional studies of Burkholderia cenocepacia D-glycero-beta-D-manno-heptose 7-phosphate kinase (HldA) and characterization of inhibitors with antibiotic adjuvant and antivirulence properties. Lee, T.W., Verhey, T.B., Antiperovitch, P.A., Atamanyuk, D., Desroy, N., Oliveira, C., Denis, A., Gerusz, V., Drocourt, E., Loutet, S.A., Hamad, M.A., Stanetty, C., Andres, S.N., Sugiman-Marangos, S., Kosma, P., Valvano, M.A., Moreau, F., Junop, M.S. J.Med.Chem.