CATH Classification

Domain Context

CATH Clusters

Superfamily UDP-galactose 4-epimerase, domain 1
Functional Family GDP-L-fucose synthase 1

Enzyme Information

1.1.1.271
GDP-L-fucose synthase.
based on mapping to UniProt Q13630
GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH.
-!- Both human and Escherichia coli enzymes can use NADH in place of NADPH to a slight extent.

UniProtKB Entries (1)

Q13630
FCL_HUMAN
Homo sapiens
GDP-L-fucose synthase

PDB Structure

PDB 4E5Y
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human FX protein, the key enzyme in the biosynthesis of GDP-L-fucose
Zhou, H., He, J.H.
To be Published
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