CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.39 | Alpha-1-antitrypsin; domain 1 |
|
2.30.39.10 | Alpha-1-antitrypsin, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Alpha-1-antitrypsin, domain 1 |
| Functional Family | Glia-derived nexin isoform 2 |
Enzyme Information
UniProtKB Entries (1)
| P00734 |
THRB_HUMAN
Homo sapiens
Prothrombin
|
PDB Structure
| PDB | 4DY7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism.
Blood
|
