CATH Domain 4dpgA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.930	BirA Bifunctional Protein; domain 2
	3.30.930.10	Bira Bifunctional Protein; Domain 2

Domain Context

CATH Clusters

Superfamily	Bira Bifunctional Protein; Domain 2
Functional Family	Lysine--tRNA ligase

Enzyme Information

2.7.7.-	Nucleotidyltransferases. based on mapping to UniProt Q15046
6.1.1.6	Lysine--tRNA ligase. based on mapping to UniProt Q15046 ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).

UniProtKB Entries (1)

SYK_HUMAN

Homo sapiens

Lysine--tRNA ligase

PDB Structure

PDB	4DPG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Switch of Lysyl-tRNA Synthetase between Translation and Transcription. Ofir-Birin, Y., Fang, P., Bennett, S.P., Zhang, H.M., Wang, J., Rachmin, I., Shapiro, R., Song, J., Dagan, A., Pozo, J., Kim, S., Marshall, A.G., Schimmel, P., Yang, X.L., Nechushtan, H., Razin, E., Guo, M. Mol.Cell