CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.630 | Cytochrome p450 |
|
1.10.630.10 | Cytochrome P450 |
Domain Context
CATH Clusters
| Superfamily | Cytochrome P450 |
| Functional Family | Cytochrome p450 CYP199A2 |
Enzyme Information
| 1.14.99.15 |
4-methoxybenzoate monooxygenase (O-demethylating).
based on mapping to UniProt Q6N8N2
4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + formaldehyde + A + H(2)O.
-!- The bacterial enzyme consists of a ferredoxin-type protein and an iron-sulfur flavoprotein (FMN). -!- Also acts on 4-ethoxybenzoate, N-methyl-4-aminobenzoate and toluate. -!- The fungal enzyme acts best on veratrate.
|
UniProtKB Entries (1)
| Q6N8N2 |
CYPA2_RHOPA
Rhodopseudomonas palustris CGA009
Cytochrome p450 CYP199A2
|
PDB Structure
| PDB | 4DNJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site
Dalton Trans
|
