CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.70 | Complement Module; domain 1 |
|
2.10.70.10 | Complement Module, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Complement Module, domain 1 |
| Functional Family | mannan-binding lectin serine protease 1 isoform X2 |
Enzyme Information
| 3.4.21.- |
Serine endopeptidases.
based on mapping to UniProt P48740
|
UniProtKB Entries (1)
| P48740 |
MASP1_HUMAN
Homo sapiens
Mannan-binding lectin serine protease 1
|
PDB Structure
| PDB | 4DJZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
J.Biol.Chem.
|