CATH Classification

Domain Context

CATH Clusters

Superfamily Collagenase (Catalytic Domain)
Functional Family Disintegrin and metalloproteinase domain-containing protein 22

Enzyme Information

3.4.24.-
Metalloendopeptidases.
based on mapping to UniProt P78325

UniProtKB Entries (1)

P78325
ADAM8_HUMAN
Homo sapiens
Disintegrin and metalloproteinase domain-containing protein 8

PDB Structure

PDB 4DD8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human ADAM-8 catalytic domain complexed with batimastat.
Hall, T., Shieh, H.S., Day, J.E., Caspers, N., Chrencik, J.E., Williams, J.M., Pegg, L.E., Pauley, A.M., Moon, A.F., Krahn, J.M., Fischer, D.H., Kiefer, J.R., Tomasselli, A.G., Zack, M.D.
Acta Crystallogr.,Sect.F