CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Ribosomal RNA large subunit methyltransferase G |
Enzyme Information
| 2.1.1.174 |
23S rRNA (guanine(1835)-N(2))-methyltransferase.
based on mapping to UniProt P42596
S-adenosyl-L-methionine + guanine(1835) in 23S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(1835) in 23S rRNA.
-!- The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. -!- The enzyme specifically methylates guanine(1835) at N(2) in 23S rRNA. -!- Formerly EC 2.1.1.52.
|
UniProtKB Entries (1)
| P42596 |
RLMG_ECOLI
Escherichia coli K-12
Ribosomal RNA large subunit methyltransferase G
|
PDB Structure
| PDB | 4DCM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural insights into the function of 23S rRNA methyltransferase RlmG (m2G1835) from Escherichia coli.
Rna
|
