CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | Pyridoxal phosphate-dependent aminotransferase |
Enzyme Information
| 2.6.1.2 |
Alanine transaminase.
based on mapping to UniProt P0A959
L-alanine + 2-oxoglutarate = pyruvate + L-glutamate.
-!- 2-aminobutanoate acts slowly instead of alanine.
|
UniProtKB Entries (1)
| P0A959 |
ALAA_ECOLI
Escherichia coli K-12
Glutamate-pyruvate aminotransferase AlaA
|
PDB Structure
| PDB | 4CVQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli.
PLoS ONE
|