CATH Domain 4cf7A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Adenylate kinase mitochondrial

Enzyme Information

2.7.4.3

Adenylate kinase.

based on mapping to UniProt O66490

ATP + AMP = 2 ADP.

-!- Inorganic triphosphate can also act as donor.

UniProtKB Entries (1)

KAD_AQUAE

Aquifex aeolicus VF5

Adenylate kinase

PDB Structure

PDB	4CF7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Energy Landscape of Adenylate Kinase During Catalysis. Kerns, S.J., Agafonov, R.V., Cho, Y., Pontiggia, F., Otten, R., Pachov, D.V., Kutter, S., Phung, L.A., Murphy, P.N., Thai, V., Alber, T., Hagan, M.F., Kern, D. Nat.Struct.Mol.Biol.