CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family probable histone-lysine N-methyltransferase PRDM7

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q96EQ9
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (2)

Q96EQ9
PRDM9_MOUSE
Mus musculus
Histone-lysine N-methyltransferase PRDM9
P68431
H31_HUMAN
Homo sapiens
Histone H3.1

PDB Structure

PDB 4C1Q
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of Prdm9.
Wu, H., Mathioudakis, N., Diagouraga, B., Dong, A., Dombrovski, L., Baudat, F., Cusack, S., De Massy, B., Kadlec, J.
Cell Rep.
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