CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.25 | UDP-galactose 4-epimerase; domain 1 |
|
3.90.25.10 | UDP-galactose 4-epimerase, domain 1 |
Domain Context
CATH Clusters
| Superfamily | UDP-galactose 4-epimerase, domain 1 |
| Functional Family | GDP-L-fucose synthase 1 |
Enzyme Information
| 1.1.1.271 |
GDP-L-fucose synthase.
based on mapping to UniProt Q13630
GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH.
-!- Both human and Escherichia coli enzymes can use NADH in place of NADPH to a slight extent.
|
UniProtKB Entries (1)
| Q13630 |
FCL_HUMAN
Homo sapiens
GDP-L-fucose synthase
|
PDB Structure
| PDB | 4B8W |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Human Gdp-L-Fucose Synthase with Bound Nadp and Gdp, Tetragonal Crystal Form
To be Published
|