1 keywords

CATH Domain 4af0A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

UniProtKB Entries (1)

E3P6S0
E3P6S0_CRYNE
Cryptococcus neoformans
Inosine-5'-monophosphate dehydrogenase

PDB Structure

PDB 4AF0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
De Novo GTP Biosynthesis is Critical for Virulence of the Fungal Pathogen Cryptococcus Neoformans
Morrow, C.A., Valkov, E., Stamp, A., Chow, E.W.L., Lee, I.R., Wronski, A., Williams, S.J., Hill, J.M., Djordjevic, J.T., Kappler, U., Kobe, B., Fraser, J.A.
Plos Pathog.