CATH Classification

Domain Context

CATH Clusters

Superfamily 1.25.40.430
Functional Family Mitotic checkpoint serine/threonine-protein kinase BUB1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O43683
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O43683
BUB1_HUMAN
Homo sapiens
Mitotic checkpoint serine/threonine-protein kinase BUB1

PDB Structure

PDB 4A1G
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis Reveals Features of the Spindle Checkpoint Kinase Bub1-Kinetochore Subunit Knl1 Interaction.
Krenn, V., Wehenkel, A., Li, X., Santaguida, S., Musacchio, A.
J.Cell Biol.