CATH Domain 3zxhA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.390	Collagenase (Catalytic Domain)
	3.40.390.10	Collagenase (Catalytic Domain)

Domain Context

CATH Clusters

Superfamily	Collagenase (Catalytic Domain)
Functional Family	Collagenase 3

Enzyme Information

3.4.24.-

Metalloendopeptidases.

based on mapping to UniProt P45452

UniProtKB Entries (1)

MMP13_HUMAN

Homo sapiens

Collagenase 3

PDB Structure

PDB	3ZXH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Potent and Selective 2-Naphthylsulfonamide Substituted Hydroxamic Acid Inhibitors of Matrix Metalloproteinase-13. Tommasi, R.A., Weiler, S., Mcquire, L.W., Rogel, O., Chambers, M., Clark, K.L., Doughty, J., Fang, J., Ganu, V., Grob, J., Goldberg, R., Goldstein, R., Lavoie, S., Kulathila, R., Macchia, W., Melton, R., Springer, C., Walker, M., Zhang, J., Zhu, L., Shultz, M. Bioorg.Med.Chem.Lett.