CATH Domain 3zsyB00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.10	Ribonuclease H-like superfamily/Ribonuclease H

Domain Context

CATH Clusters

Superfamily	Ribonuclease H-like superfamily/Ribonuclease H
Functional Family	POL polyprotein

Enzyme Information

UniProtKB Entries (1)

Q76353_9HIV1

Human immunodeficiency virus 1

Integrase

PDB Structure

PDB	3ZSY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design. Peat, T.S., Rhodes, D.I., Vandegraaff, N., Le, G., Smith, J.A., Clark, L.J., Jones, E.D., Coates, J.A.V., Thienthong, N., Newman, J., Dolezal, O., Mulder, R., Ryan, J.H., Savage, G.P., Francis, C.L., Deadman, J.J. Plos One