CATH Domain 3zm9A02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.1200	Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2
	3.90.1200.10	Aminoglycoside phosphotransferase (APH), C-terminal lobe

Domain Context

CATH Clusters

Superfamily	3.90.1200.10
Functional Family	Choline kinase alpha

Enzyme Information

2.7.1.82	Ethanolamine kinase. based on mapping to UniProt P35790 ATP + ethanolamine = ADP + O-phosphoethanolamine.
2.7.1.32	Choline kinase. based on mapping to UniProt P35790 ATP + choline = ADP + phosphocholine. -!- Ethanolamine and its methyl and ethyl derivatives can also act as acceptors.

UniProtKB Entries (1)

CHKA_HUMAN

Homo sapiens

Choline kinase alpha

PDB Structure

PDB	3ZM9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Mechanism of Allosteric Coupling in Choline Kinase A1 Revealed by a Rationally Designed Inhibitor Sahun-Roncero, M., Rubio-Ruiz, B., Saladino, G., Conejo-Garcia, A., Espinosa, A., Velazquez-Campoy, A., Gervasio, F.L., Entrena, A., Hurtado-Guerrero, R. Angew.Chem.Int.Ed.Engl.