CATH Domain 3wcaA00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.600	Farnesyl Diphosphate Synthase
	1.10.600.10	Farnesyl Diphosphate Synthase

Domain Context

CATH Clusters

Superfamily	Farnesyl Diphosphate Synthase
Functional Family	Farnesyl-diphosphate farnesyltransferase 1

Enzyme Information

UniProtKB Entries (1)

Q4CWB4_TRYCC

Trypanosoma cruzi strain CL Brener

Farnesyltransferase, putative

PDB Structure

PDB	3WCA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Squalene synthase as a target for Chagas disease therapeutics. Shang, N., Li, Q., Ko, T.P., Chan, H.C., Li, J., Zheng, Y., Huang, C.H., Ren, F., Chen, C.C., Zhu, Z., Galizzi, M., Li, Z.H., Rodrigues-Poveda, C.A., Gonzalez-Pacanowska, D., Veiga-Santos, P., de Carvalho, T.M., de Souza, W., Urbina, J.A., Wang, A.H., Docampo, R., Li, K., Liu, Y.L., Oldfield, E., Guo, R.T. Plos Pathog.