CATH Classification

Domain Context

CATH Clusters

Superfamily Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
Functional Family Histone-lysine N-methyltransferase SETD7

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8WTS6
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q8WTS6
SETD7_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase SETD7

PDB Structure

PDB 3VV0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of histone methyltransferase SET7/9 in complexes with adenosylmethionine derivatives
Niwa, H., Handa, N., Tomabechi, Y., Honda, K., Toyama, M., Ohsawa, N., Shirouzu, M., Kagechika, H., Hirano, T., Umehara, T., Yokoyama, S.
Acta Crystallogr.,Sect.D
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