CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.90 | Alpha-Beta Complex |
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3.90.226 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
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3.90.226.10 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Domain Context
CATH Clusters
Superfamily | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Functional Family | ATP-dependent Clp protease proteolytic subunit |
Enzyme Information
3.4.21.92 |
Endopeptidase Clp.
based on mapping to UniProt Q2G036
Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
-!- Belongs to peptidase family S14.
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UniProtKB Entries (1)
Q2G036 |
CLPP_STAA8
Staphylococcus aureus subsp. aureus NCTC 8325
ATP-dependent Clp protease proteolytic subunit
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PDB Structure
PDB | 3V5I |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Insights into structural network responsible for oligomerization and activity of bacterial virulence regulator caseinolytic protease P (ClpP) protein.
J.Biol.Chem.
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