CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.120 | Enolase-like C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Enolase-like C-terminal domain |
| Functional Family | Enolase 1 |
Enzyme Information
| 4.2.1.11 |
Phosphopyruvate hydratase.
based on mapping to UniProt P09104
2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.
-!- Also acts on 3-phospho-D-erythronate.
|
UniProtKB Entries (1)
| P09104 |
ENOG_HUMAN
Homo sapiens
Gamma-enolase
|
PDB Structure
| PDB | 3UJF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem.
|
