CATH Domain 3u2qA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Elongation factor Tu

Enzyme Information

UniProtKB Entries (1)

EFTU1_ECOLI

Escherichia coli K-12

Elongation factor Tu 1

PDB Structure

PDB	3U2Q
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovery of LFF571: an investigational agent for Clostridium difficile infection. LaMarche, M.J., Leeds, J.A., Amaral, A., Brewer, J.T., Bushell, S.M., Deng, G., Dewhurst, J.M., Ding, J., Dzink-Fox, J., Gamber, G., Jain, A., Lee, K., Lee, L., Lister, T., McKenney, D., Mullin, S., Osborne, C., Palestrant, D., Patane, M.A., Rann, E.M., Sachdeva, M., Shao, J., Tiamfook, S., Trzasko, A., Whitehead, L., Yifru, A., Yu, D., Yan, W., Zhu, Q. J.Med.Chem.