CATH Classification

Domain Context

CATH Clusters

Superfamily 3.90.950.10
Functional Family dITP/XTP pyrophosphatase

Enzyme Information

3.6.1.66
XTP/dITP diphosphatase.
based on mapping to UniProt Q83FA3
(1) XTP + H(2)O = XMP + diphosphate. (2) dITP + H(2)O = dIMP + diphosphate. (3) ITP + H(2)O = IMP + diphosphate.
-!- The enzymes from the bacterium Escherichia coli and the archaea Methanococcus jannaschii and Archaeoglobus fulgidus are highly specific for XTP, dITP and ITP.

UniProtKB Entries (1)

Q83FA3
IXTPA_COXBU
Coxiella burnetii RSA 493
DITP/XTP pyrophosphatase

PDB Structure

PDB 3TQU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural genomics for drug design against the pathogen Coxiella burnetii.
Franklin, M.C., Cheung, J., Rudolph, M.J., Burshteyn, F., Cassidy, M., Gary, E., Hillerich, B., Yao, Z.K., Carlier, P.R., Totrov, M., Love, J.D.
Proteins
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