CATH Domain 3to6A03

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	Histone acetyltransferase

2.3.1.48

Histone acetyltransferase.

based on mapping to UniProt Q08649

Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.

-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

ESA1_YEAST

Saccharomyces cerevisiae S288C

Histone acetyltransferase ESA1

PDB	3TO6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	MYST protein acetyltransferase activity requires active site lysine autoacetylation. Yuan, H., Rossetto, D., Mellert, H., Dang, W., Srinivasan, M., Johnson, J., Hodawadekar, S., Ding, E.C., Speicher, K., Abshiru, N., Perry, R., Wu, J., Yang, C., Zheng, Y.G., Speicher, D.W., Thibault, P., Verreault, A., Johnson, F.B., Berger, S.L., Sternglanz, R., McMahon, S.B., Cote, J., Marmorstein, R. Embo J.