CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.50 | 3-Layer(bba) Sandwich | |
3.50.30 | Glucose Oxidase; domain 1 | |
3.50.30.10 | Phosphohistidine domain |
Domain Context
CATH Clusters
Superfamily | Phosphohistidine domain |
Functional Family | Pyruvate kinase |
Enzyme Information
2.7.1.40 |
Pyruvate kinase.
based on mapping to UniProt Q6GG09
ATP + pyruvate = ADP + phosphoenolpyruvate.
-!- UTP, GTP, CTP, ITP and dATP can also act as donors. -!- Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).
|
UniProtKB Entries (1)
Q6GG09 |
KPYK_STAAR
Staphylococcus aureus subsp. aureus MRSA252
Pyruvate kinase
|
PDB Structure
PDB | 3T0T |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase.
Acs Chem.Biol.
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