CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.10 | Roll |
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3.10.450 | Nuclear Transport Factor 2; Chain: A, |
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3.10.450.40 |
Domain Context
CATH Clusters
Superfamily | 3.10.450.40 |
Functional Family |
Enzyme Information
1.4.3.21 |
Primary-amine oxidase.
based on mapping to UniProt P12807
RCH(2)NH(2) + H(2)O + O(2) = RCHO + NH(3) + H(2)O(2).
-!- A group of enzymes that oxidize primary monoamines but have little or no activity toward diamines, such as histamine, or toward secondary and tertiary amines. -!- They are copper quinoproteins (2,4,5-trihydroxyphenylalanine quinone) and, unlike EC 1.4.3.4, are sensitive to inhibition by carbonyl-group reagents, such as semicarbazide. -!- In some mammalian tissues the enzyme also functions as a vascular- adhesion protein (VAP-1). -!- Formerly EC 1.4.3.6.
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UniProtKB Entries (1)
P12807 |
AMO_PICAN
Ogataea angusta
Peroxisomal primary amine oxidase
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PDB Structure
PDB | 3SX1 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The precursor form of Hansenula polymorpha copper amine oxidase 1 in complex with CuI and CoII.
Acta Crystallogr.,Sect.F
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