CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.238.210
Functional Family Glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2
Glutaminase.
based on mapping to UniProt D3Z7P3
L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

D3Z7P3
GLSK_MOUSE
Mus musculus
Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB 3SS4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Cassago, A., Ferreira, A.P., Ferreira, I.M., Fornezari, C., Gomes, E.R., Greene, K.S., Pereira, H.M., Garratt, R.C., Dias, S.M., Ambrosio, A.L.
Proc.Natl.Acad.Sci.USA
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