CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.2000 | Glycogen Phosphorylase B; |
Domain Context
CATH Clusters
| Superfamily | Glycogen Phosphorylase B; |
| Functional Family | Glycogen [starch] synthase |
Enzyme Information
| 2.4.1.11 |
Glycogen(starch) synthase.
based on mapping to UniProt P27472
UDP-alpha-D-glucose + ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha- D-glucosyl)(n+1).
-!- The description (official name) varies according to the source of the enzyme and the nature of its synthetic product. -!- Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin. -!- The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186. -!- A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21).
|
UniProtKB Entries (1)
| P27472 |
GYS2_YEAST
Saccharomyces cerevisiae S288C
Glycogen [starch] synthase isoform 2
|
PDB Structure
| PDB | 3RT1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen.
J.Biol.Chem.
|
