CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1190 | UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase |
|
3.40.1190.20 | Ribokinase |
Domain Context
CATH Clusters
| Superfamily | 3.40.1190.20 |
| Functional Family | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20 |
Enzyme Information
| 2.7.4.7 |
Phosphooxymethylpyrimidine kinase.
based on mapping to UniProt Q08224
ATP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine = ADP + 4-amino-2- methyl-5-(diphosphooxymethyl)pyrimidine.
|
| 2.7.1.49 |
Hydroxymethylpyrimidine kinase.
based on mapping to UniProt Q08224
ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine = ADP + 4-amino-2- methyl-5-(phosphomethyl)pyrimidine.
-!- CTP, UTP and GTP can act as donors.
|
UniProtKB Entries (1)
| Q08224 |
THI20_YEAST
Saccharomyces cerevisiae S288C
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20
|
PDB Structure
| PDB | 3RM5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of trifunctional THI20 from yeast.
Acta Crystallogr.,Sect.D
|