CATH Classification

Domain Context

CATH Clusters

Superfamily L-arginine/glycine Amidinotransferase; Chain A
Functional Family N(G),N(G)-dimethylarginine dimethylaminohydrolase

Enzyme Information

3.5.3.18
Dimethylargininase.
based on mapping to UniProt Q9I4E3
N(omega),N(omega)-dimethyl-L-arginine + H(2)O = dimethylamine + L-citrulline.
-!- Also acts on N(omega)-methyl-L-arginine.

UniProtKB Entries (1)

Q9I4E3
DDAH_PSEAE
Pseudomonas aeruginosa PAO1
N(G),N(G)-dimethylarginine dimethylaminohydrolase

PDB Structure

PDB 3RHY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
On the mechanism of dimethylarginine dimethylaminohydrolase inactivation by 4-halopyridines.
Johnson, C.M., Monzingo, A.F., Ke, Z., Yoon, D.W., Linsky, T.W., Guo, H., Robertus, J.D., Fast, W.
J.Am.Chem.Soc.