CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.40 | 3-Layer(aba) Sandwich |
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3.40.309 | Aldehyde Dehydrogenase; Chain A, domain 2 |
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3.40.309.10 | Aldehyde Dehydrogenase; Chain A, domain 2 |
Domain Context
CATH Clusters
Superfamily | Aldehyde Dehydrogenase; Chain A, domain 2 |
Functional Family | Cytosolic 10-formyltetrahydrofolate dehydrogenase |
Enzyme Information
1.5.1.6 |
Formyltetrahydrofolate dehydrogenase.
based on mapping to UniProt P28037
10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.
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UniProtKB Entries (1)
P28037 |
AL1L1_RAT
Rattus norvegicus
Cytosolic 10-formyltetrahydrofolate dehydrogenase
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PDB Structure
PDB | 3RHM |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem.
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