CATH Classification

Domain Context

CATH Clusters

Superfamily Chorismate mutase
Functional Family Isochorismate pyruvate lyase

Enzyme Information

5.4.99.5
Chorismate mutase.
based on mapping to UniProt Q51507
Chorismate = prephenate.
4.2.99.21
Isochorismate lyase.
based on mapping to UniProt Q51507
Isochorismate = salicylate + pyruvate.
-!- This enzyme is part of the pathway of salicylate formation from chorismate, and forms an integral part of pathways that produce salicylate-derived siderophores, such as pyochelin and yersiniabactin.

UniProtKB Entries (1)

Q51507
PCHB_PSEAE
Pseudomonas aeruginosa PAO1
Isochorismate pyruvate lyase

PDB Structure

PDB 3REM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
pH Dependence of Catalysis by Pseudomonas aeruginosa Isochorismate-Pyruvate Lyase: Implications for Transition State Stabilization and the Role of Lysine 42.
Olucha, J., Ouellette, A.N., Luo, Q., Lamb, A.L.
Biochemistry