CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family |
Enzyme Information
| 1.1.1.384 |
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase.
based on mapping to UniProt B3TMR8
dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP(+) = dTDP-3,4- didehydro-2,6-dideoxy-alpha-D-glucose + NADPH.
-!- The enzyme is involved in the biosynthesis of several deoxysugars, including L-digitoxose, L- and D-olivose, L-oliose, D-mycarose and forosamine.
|
UniProtKB Entries (1)
| B3TMR8 |
KIJDR_ACTKI
Actinomadura kijaniata
DTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
|
PDB Structure
| PDB | 3RCB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Combined Structural and Functional Investigation of a C-3''-Ketoreductase Involved in the Biosynthesis of dTDP-l-Digitoxose.
Biochemistry
|
