CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa constant

Enzyme Information

UniProtKB Entries (1)

P56817
BACE1_HUMAN
Homo sapiens
Beta-secretase 1

PDB Structure

PDB 3R1G
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-{beta} Production in Vivo.
Atwal, J.K., Chen, Y., Chiu, C., Mortensen, D.L., Meilandt, W.J., Liu, Y., Heise, C.E., Hoyte, K., Luk, W., Lu, Y., Peng, K., Wu, P., Rouge, L., Zhang, Y., Lazarus, R.A., Scearce-Levie, K., Wang, W., Wu, Y., Tessier-Lavigne, M., Watts, R.J.
Sci Transl Med
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