CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.930 | BirA Bifunctional Protein; domain 2 | |
3.30.930.10 | Bira Bifunctional Protein; Domain 2 |
Domain Context
CATH Clusters
Superfamily | Bira Bifunctional Protein; Domain 2 |
Functional Family | Seryl-tRNA synthetase, cytoplasmic |
Enzyme Information
6.1.1.11 |
Serine--tRNA ligase.
based on mapping to UniProt Q9HGT6
(1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec).
-!- This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1.
|
UniProtKB Entries (1)
Q9HGT6 |
SYSC_CANAL
Candida albicans SC5314
Serine--tRNA ligase, cytoplasmic
|
PDB Structure
PDB | 3QNE |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen.
Proc.Natl.Acad.Sci.USA
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