CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.430 | Dihydrofolate Reductase, subunit A |
|
3.40.430.10 | Dihydrofolate Reductase, subunit A |
Domain Context
CATH Clusters
| Superfamily | Dihydrofolate Reductase, subunit A |
| Functional Family |
Enzyme Information
UniProtKB Entries (1)
| Q6FPH0 |
Q6FPH0_CANGA
[Candida] glabrata CBS 138
Uncharacterized protein
|
PDB Structure
| PDB | 3QLX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures of Candida albicans Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal the Flexibility of Active Site Loop Residues Critical for Ligand Potency and Selectivity.
Chem.Biol.Drug Des.
|
