CATH Domain 3ql0A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.430	Dihydrofolate Reductase, subunit A
	3.40.430.10	Dihydrofolate Reductase, subunit A

Domain Context

CATH Clusters

Superfamily	Dihydrofolate Reductase, subunit A
Functional Family	Dihydrofolate reductase

Enzyme Information

UniProtKB Entries (1)

Q1RGF0_ECOUT

Escherichia coli UTI89

Dihydrofolate reductase

PDB Structure

PDB	3QL0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysis. Bhabha, G., Lee, J., Ekiert, D.C., Gam, J., Wilson, I.A., Dyson, H.J., Benkovic, S.J., Wright, P.E. Science