CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.420 | Nucleotidyltransferase; domain 5 | |
3.30.420.40 | ATPase, nucleotide binding domain |
Domain Context
CATH Clusters
Superfamily | 3.30.420.40 |
Functional Family | Endoplasmic reticulum chaperone BiP |
Enzyme Information
3.6.4.10 |
Non-chaperonin molecular chaperone ATPase.
based on mapping to UniProt P16474
ATP + H(2)O = ADP + phosphate.
-!- This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. -!- They comprise a number of heat-shock-cognate proteins. -!- They are also active in clathrin uncoating and in the oligomerization of actin.
|
UniProtKB Entries (1)
P16474 |
BIP_YEAST
Saccharomyces cerevisiae S288C
Endoplasmic reticulum chaperone BiP
|
PDB Structure
PDB | 3QFP |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J.
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