CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.40 | ATPase, nucleotide binding domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.420.40 |
| Functional Family |
Enzyme Information
| 2.7.1.170 |
Anhydro-N-acetylmuramic acid kinase.
based on mapping to UniProt Q9I5Q5
ATP + 1,6-anhydro-N-acetyl-beta-muramate + H(2)O = ADP + N-acetylmuramate 6-phosphate.
-!- This enzyme, along with EC 4.2.1.126, is required for the utilization of anhydro-N-acetylmuramic acid in proteobacteria. -!- The substrate is either imported from the medium or derived from the bacterium's own cell wall murein during cell wall recycling. -!- The product N-acetylmuramate 6-phosphate is produced as a 7:1 mixture of the alpha- and beta-anomers. -!- Formerly EC 2.7.1.n1.
|
UniProtKB Entries (1)
| Q9I5Q5 |
ANMK_PSEAE
Pseudomonas aeruginosa PAO1
Anhydro-N-acetylmuramic acid kinase
|
PDB Structure
| PDB | 3QBX |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Molecular Basis of 1,6-Anhydro Bond Cleavage and Phosphoryl Transfer by Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase.
J.Biol.Chem.
|