CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Aurora kinase A

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O14965
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O14965
AURKA_HUMAN
Homo sapiens
Aurora kinase A

PDB Structure

PDB 3QBN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of Ustilago maydis Aurora kinase as a novel antifungal target.
Tueckmantel, S., Greul, J.N., Janning, P., Brockmeyer, A., Gruetter, C., Simard, J.R., Gutbrod, O., Beck, M.E., Tietjen, K., Rauh, D., Schreier, P.H.
Acs Chem.Biol.