CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.850 | Isochorismatase-like |
Domain Context
CATH Clusters
| Superfamily | Isochorismatase-like |
| Functional Family | Pyrazinamidase/nicotinamidase PncA |
Enzyme Information
| 3.5.1.- |
In linear amides.
based on mapping to UniProt Q50575
|
| 3.5.1.19 |
Nicotinamidase.
based on mapping to UniProt Q50575
Nicotinamide + H(2)O = nicotinate + NH(3).
|
UniProtKB Entries (1)
| Q50575 |
Q50575_MYCTX
Mycobacterium tuberculosis
Pyrazinamidase
|
PDB Structure
| PDB | 3PL1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of the Pyrazinamidase of Mycobacterium tuberculosis: Insights into Natural and Acquired Resistance to Pyrazinamide.
Plos One
|