CATH Classification

Domain Context

CATH Clusters

Superfamily Leucine Dehydrogenase, chain A, domain 1
Functional Family Shikimate dehydrogenase (NADP(+))

Enzyme Information

1.1.1.25
Shikimate dehydrogenase.
based on mapping to UniProt Q9KVT3
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.

UniProtKB Entries (1)

Q9KVT3
AROE_VIBCH
Vibrio cholerae O1 biovar El Tor str. N16961
Shikimate dehydrogenase (NADP(+))

PDB Structure

PDB 3PGJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
2.49 Angstrom resolution crystal structure of shikimate 5-dehydrogenase (aroE) from Vibrio cholerae O1 biovar eltor str. N16961 in complex with shikimate
Halavaty, A.S., Light, S.H., Shuvalova, L., Papazisi, L., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
To be Published
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