CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Glyceraldehyde-3-phosphate dehydrogenase |
Enzyme Information
| 1.2.1.12 |
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
based on mapping to UniProt O14556
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
-!- Also acts very slowly on D-glyceraldehyde and some other aldehydes. -!- Thiols can replace phosphate.
|
UniProtKB Entries (1)
| O14556 |
G3PT_HUMAN
Homo sapiens
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific
|
PDB Structure
| PDB | 3PFW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS.
Biochem.J.
|
