CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.40 | Immunoglobulin-like | |
2.60.40.180 | Transthyretin/hydroxyisourate hydrolase domain |
Domain Context
CATH Clusters
Superfamily | Transthyretin/hydroxyisourate hydrolase domain |
Functional Family | Transthyretin |
Enzyme Information
UniProtKB Entries (1)
P02766 |
TTHY_HUMAN
Homo sapiens
Transthyretin
|
PDB Structure
PDB | 3P3R |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Sci Transl Med
|