CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1170 | MutS, DNA mismatch repair protein, domain I |
|
3.40.1170.20 | tRNA intron endonuclease, N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | tRNA intron endonuclease, N-terminal domain |
| Functional Family |
Enzyme Information
| 4.6.1.16 |
tRNA-intron lyase.
based on mapping to UniProt O29362
PretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
-!- The enzyme catalyzes the final stage in the maturation of tRNA molecules. -!- Formerly EC 3.1.27.9.
|
| 4.6.1.16 |
tRNA-intron lyase.
based on mapping to UniProt Q9YBF1
PretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
-!- The enzyme catalyzes the final stage in the maturation of tRNA molecules. -!- Formerly EC 3.1.27.9.
|
UniProtKB Entries (2)
| Q9YBF1 |
ENDA_AERPE
Aeropyrum pernix K1
TRNA-splicing endonuclease
|
| O29362 |
ENDA_ARCFU
Archaeoglobus fulgidus DSM 4304
TRNA-splicing endonuclease
|
PDB Structure
| PDB | 3P1Y |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Cleavage of intron from the standard or non-standard position of the precursor tRNA by the splicing endonuclease of Aeropyrum pernix, a hyper-thermophilic Crenarchaeon, involves a novel RNA recognition site in the Crenarchaea specific loop
Nucleic Acids Res.
|