CATH Classification

Domain Context

CATH Clusters

Superfamily Hexapeptide repeat proteins
Functional Family Carbonic anhydrase

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P40881
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P40881
CAH_METTE
Methanosarcina thermophila
Carbonic anhydrase

PDB Structure

PDB 3OTM
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of gamma-carbonic anhydrase mutants from Methanosarcina thermophila
Domsic, J.F., Robbins, A.H., McKenna, R.
To be Published