CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.270
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q04049
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q04049
POLH_YEAST
Saccharomyces cerevisiae S288C
DNA polymerase eta

PDB Structure

PDB 3OHA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta.
Silverstein, T.D., Jain, R., Johnson, R.E., Prakash, L., Prakash, S., Aggarwal, A.K.
Structure
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