CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Methylase, subunit A, domain 2
Functional Family

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P05102
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

P05102
MTH1_HAEPH
Haemophilus parahaemolyticus
Modification methylase HhaI

PDB Structure

PDB 3MHT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
O'Gara, M., Klimasauskas, S., Roberts, R.J., Cheng, X.
J.Mol.Biol.
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